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Lingyi Kong Selected Research

oren gedoku to

1/20191H NMR-Based Metabolomics Reveals Refined-Huang-Lian-Jie-Du-Decoction (BBG) as a Potential Ischemic Stroke Treatment Drug With Efficacy and a Favorable Therapeutic Window.
10/2017Comparative study of single/combination use of Huang-Lian-Jie-Du decoction and berberine on their protection on sepsis induced acute liver injury by NMR metabolic profiling.
7/2017Deciphering the mechanism of Huang-Lian-Jie-Du-Decoction on the treatment of sepsis by formula decomposition and metabolomics: Enhancement of cholinergic pathways and inhibition of HMGB-1/TLR4/NF-κB signaling.
1/2017Treatment Effects of Ischemic Stroke by Berberine, Baicalin, and Jasminoidin from Huang-Lian-Jie-Du-Decoction (HLJDD) Explored by an Integrated Metabolomics Approach.
1/2017Optimization of Huang-Lian-Jie-Du-Decoction for Ischemic Stroke Treatment and Mechanistic Study by Metabolomic Profiling and Network Analysis.
12/2016The components of Huang-Lian-Jie-Du-Decoction act synergistically to exert protective effects in a rat ischemic stroke model.

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Lingyi Kong Research Topics

Disease

42Neoplasms (Cancer)
08/2022 - 01/2009
10Inflammation (Inflammations)
07/2022 - 05/2012
8Breast Neoplasms (Breast Cancer)
10/2021 - 12/2015
6Colitis
01/2021 - 12/2014
5Carcinogenesis
01/2022 - 06/2016
5Ischemic Stroke
01/2022 - 12/2016
5Alzheimer Disease (Alzheimer's Disease)
12/2021 - 02/2017
5Colorectal Neoplasms (Colorectal Cancer)
12/2021 - 06/2016
5Sepsis (Septicemia)
11/2020 - 07/2016
4Osteosarcoma (Osteogenic Sarcoma)
12/2021 - 01/2015
4Liver Cirrhosis (Hepatic Cirrhosis)
01/2021 - 11/2020
4Neoplasm Metastasis (Metastasis)
01/2021 - 12/2017
3Non-alcoholic Fatty Liver Disease
07/2022 - 01/2021
3Myeloid Leukemia (Leukemia, Myelocytic)
05/2022 - 01/2017
3Mitochondrial Diseases (Mitochondrial Disease)
01/2022 - 01/2015
3Stroke (Strokes)
01/2022 - 01/2017
3Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
01/2022 - 12/2016
3Triple Negative Breast Neoplasms
05/2021 - 10/2018
3Experimental Arthritis
05/2015 - 01/2015
2Neuroinflammatory Diseases
01/2022 - 02/2017
2Hepatocellular Carcinoma (Hepatoma)
06/2021 - 01/2019
2Neurodegenerative Diseases (Neurodegenerative Disease)
01/2021 - 10/2020
2Glioma (Gliomas)
01/2021 - 01/2017
2Fibrosis (Cirrhosis)
01/2021 - 11/2020
2Colonic Neoplasms (Colon Cancer)
10/2020 - 06/2016
2Type 2 Diabetes Mellitus (MODY)
07/2018 - 08/2014
2Memory Disorders (Memory Loss)
02/2017 - 03/2013
2Infarction (Infarctions)
01/2017 - 12/2016
2Neurologic Manifestations (Neurological Manifestations)
01/2017 - 12/2016
2Leukemia
01/2017 - 06/2013
2Parkinson Disease (Parkinson's Disease)
11/2016 - 11/2014
2Body Weight (Weight, Body)
04/2016 - 12/2014
2Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
04/2016 - 09/2015
2Rheumatoid Arthritis
05/2015 - 03/2015
2Arthritis (Polyarthritis)
05/2015 - 03/2015
1Tuberous Sclerosis (Bourneville's Disease)
07/2022

Drug/Important Bio-Agent (IBA)

20Pharmaceutical PreparationsIBA
10/2021 - 08/2014
10Proteins (Proteins, Gene)FDA Link
07/2022 - 05/2012
6EnzymesIBA
01/2022 - 01/2019
6oren gedoku toIBA
01/2019 - 12/2016
5Reactive Oxygen Species (Oxygen Radicals)IBA
01/2022 - 09/2015
5AntioxidantsIBA
10/2021 - 12/2016
5Biological ProductsIBA
10/2020 - 12/2017
5Dextran SulfateIBA
01/2018 - 12/2014
4Liposomes (Liposome)IBA
02/2022 - 12/2015
4Therapeutic UsesIBA
01/2021 - 01/2015
3LipidsIBA
07/2022 - 12/2015
3Biomarkers (Surrogate Marker)IBA
07/2022 - 08/2019
3wogoninIBA
05/2022 - 01/2017
3Glutathione (Reduced Glutathione)IBA
01/2022 - 05/2013
3Amyloid (Amyloid Fibrils)IBA
01/2022 - 01/2018
3STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
12/2021 - 11/2016
3Lysine (L-Lysine)FDA Link
01/2021 - 01/2018
3Doxorubicin (Adriamycin)FDA LinkGeneric
04/2019 - 01/2015
3Amino AcidsFDA Link
01/2019 - 07/2016
3BerberineIBA
10/2017 - 12/2016
3LipopolysaccharidesIBA
02/2017 - 07/2016
3Paclitaxel (Taxol)FDA LinkGeneric
01/2017 - 12/2009
3baicalinIBA
01/2017 - 07/2016
3SaponinsIBA
03/2015 - 10/2005
2PhytochemicalsIBA
07/2022 - 01/2021
2CytokinesIBA
02/2022 - 03/2015
2InflammasomesIBA
01/2022 - 01/2021
2Histone Deacetylase InhibitorsIBA
01/2022 - 10/2021
2Histone Deacetylases (Histone Deacetylase)IBA
01/2022 - 10/2021
2DNA (Deoxyribonucleic Acid)IBA
01/2022 - 05/2012
2Phosphotransferases (Kinase)IBA
12/2021 - 01/2017
2tubocapsenolide AIBA
12/2021 - 01/2021
2withangulatin AIBA
10/2021 - 10/2020
2Glucose (Dextrose)FDA LinkGeneric
06/2021 - 07/2018
2cryptotanshinoneIBA
05/2021 - 10/2018
2ProdrugsIBA
01/2021 - 12/2019
2Small Interfering RNA (siRNA)IBA
01/2021 - 11/2017
2Hyaluronic Acid (Hyaluronan)IBA
01/2021 - 12/2015
2Transcription Factors (Transcription Factor)IBA
01/2021 - 11/2020
2graphene oxideIBA
11/2020 - 01/2018
2Endoplasmic Reticulum Chaperone BiPIBA
01/2019 - 12/2017
2Neuroprotective AgentsIBA
01/2019 - 11/2016
2Cholinergic Agents (Cholinergics)IBA
07/2017 - 03/2013
2Messenger RNA (mRNA)IBA
01/2017 - 05/2012
2geniposideIBA
01/2017 - 12/2016
2FlavonoidsIBA
09/2016 - 09/2015
2Interleukin-10 (Interleukin 10)IBA
05/2015 - 03/2015
2praeruptorin AIBA
05/2012 - 07/2010
1GSK-2816126IBA
08/2022
1tazemetostatIBA
08/2022
1Mechanistic Target of Rapamycin Complex 1IBA
07/2022
1Tripartite Motif ProteinsIBA
07/2022
1trans-sodium crocetinate (crocetin)IBA
07/2022
1DEAD-box RNA HelicasesIBA
07/2022
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
07/2022
1Leucine (L-Leucine)FDA Link
07/2022
1MicroRNAs (MicroRNA)IBA
07/2022
1Podophyllotoxin (Condylox)FDA LinkGeneric
02/2022

Therapy/Procedure

27Therapeutics
02/2022 - 12/2015
6Chinese Traditional Medicine (Traditional Chinese Medicine)
01/2019 - 07/2010
4Ligation
01/2021 - 07/2017
3Drug Therapy (Chemotherapy)
01/2021 - 01/2015
3Punctures
11/2020 - 07/2017
3Oral Administration
03/2015 - 05/2013